Release date: 2008-04-11 Successful use of endoscopes for vascular bridge collection. Dr. Liu Jincheng, Department of Cardiac Surgery, Xijing Hospital, Fourth Military Medical University, and other researchers, completed the application of endoscopic saphenous vein bridge collection in coronary artery bypass surgery for 6 years. "Project research. The study used endoscopic vascular acquisition technology to collect the saphenous vein and applied it to coronary artery bypass grafting (CABG), which achieved good clinical results. A few days ago, this research achievement won the second prize of the 2007 military medical results.
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Coronary artery bypass grafting (CABG) is one of the most effective methods for the treatment of coronary heart disease. Foreign researchers have used the endoscopic vascular acquisition technique to collect the great saphenous vein since 1998 and apply it to CABG. Since April 2000, Liu Jincheng and other researchers have used the VASOVIEW endoscope to collect the saphenous vein of the patient as a CABG vascular bridge. It has been successfully used in 196 patients with coronary artery bypass grafting and has received good clinical results. Compared with traditional surgery, the method of collecting vascular bridge by endoscope has the characteristics of small trauma, little pain and quick recovery. The incidence of postoperative lower extremity complications was 66% lower than that of the total incision, especially in patients with coronary heart disease with diabetes. The average walking time was reduced by 1.1 days compared to the conventional collection bridge group.
The study found that the application of endoscopes to collect venous bridges is significantly improved compared to traditional surgical bridges. The results of HE staining showed that the endoscopic collection of vascular bridges was more complete than the conventional methods, and there was no obvious damage to the vessel wall. The researchers also studied the mechanism of PDGFR-β antisense oligodeoxynucleotides against vascular restenosis, established an in vitro proliferation model of animal thoracic aortic vascular smooth muscle cells, and found that PDGFR-β antisense oligodeoxynucleotides promoted SMC proliferation and migration. There is significant inhibition that can induce apoptosis.
In addition, the researchers also proposed new ideas for coronary artery bypass grafting and endoscopic collection of vascular bridge postoperative care work. They also carried out perioperative psychological care for the special condition of patients with coronary heart disease, which reduced the psychological burden of patients and the impact of postoperative stress response on surgery, and the leg care of patients after endoscopic collection of vascular bridge Early activities proposed new methods. —— China Pharmaceutical 123 Network